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Acetyl-11-keto-β-boswellic acid enhances the cisplatin sensitivity of non-small cell lung cancer cells through cell cycle arrest, apoptosis induction, and autophagy suppression via p21-dependent signaling pathway

Cisplatin-based therapy is a widely used chemotherapeutic regimen for non-small cell lung cancer (NSCLC); however, drug resistance limits its efficacy. Acetyl-11-keto-β-boswellic acid (AKBA), a bioactive compound from frankincense, has been shown to exert anti-cancer effects. The aim of this study i...

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Detalles Bibliográficos
Autores principales: Lv, Minghe, Zhuang, Xibing, Zhang, Qi, Cheng, Yunfeng, Wu, Duojiao, Wang, Xiangdong, Qiao, Tiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012341/
https://www.ncbi.nlm.nih.gov/pubmed/32562082
http://dx.doi.org/10.1007/s10565-020-09541-5