Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy

Screening for effective candidate drugs for breast cancer has shifted from two-dimensional (2D) to three-dimensional (3D) cultures. Here we systematically compared the transcriptomes of these different culture conditions by RNAseq of 14 BC cell lines cultured in both 2D and 3D conditions. All 3D BC...

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Detalles Bibliográficos
Autores principales: Koedoot, Esmee, Wolters, Liesanne, Smid, Marcel, Stoilov, Peter, Burger, Gerhard A., Herpers, Bram, Yan, Kuan, Price, Leo S., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012355/
https://www.ncbi.nlm.nih.gov/pubmed/33790333
http://dx.doi.org/10.1038/s41598-021-86664-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012355/
https://www.ncbi.nlm.nih.gov/pubmed/33790333
http://dx.doi.org/10.1038/s41598-021-86664-7

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