Genome-wide binding potential and regulatory activity of the glucocorticoid receptor’s monomeric and dimeric forms

A widely regarded model for glucocorticoid receptor (GR) action postulates that dimeric binding to DNA regulates unfavorable metabolic pathways while monomeric receptor binding promotes repressive gene responses related to its anti-inflammatory effects. This model has been built upon the characteriz...

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Detalles Bibliográficos
Autores principales: Johnson, Thomas A., Paakinaho, Ville, Kim, Sohyoung, Hager, Gordon L., Presman, Diego M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012360/
https://www.ncbi.nlm.nih.gov/pubmed/33790284
http://dx.doi.org/10.1038/s41467-021-22234-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012360/
https://www.ncbi.nlm.nih.gov/pubmed/33790284
http://dx.doi.org/10.1038/s41467-021-22234-9

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