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Genome-wide binding potential and regulatory activity of the glucocorticoid receptor’s monomeric and dimeric forms
A widely regarded model for glucocorticoid receptor (GR) action postulates that dimeric binding to DNA regulates unfavorable metabolic pathways while monomeric receptor binding promotes repressive gene responses related to its anti-inflammatory effects. This model has been built upon the characteriz...
Autores principales: | Johnson, Thomas A., Paakinaho, Ville, Kim, Sohyoung, Hager, Gordon L., Presman, Diego M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012360/ https://www.ncbi.nlm.nih.gov/pubmed/33790284 http://dx.doi.org/10.1038/s41467-021-22234-9 |
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