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Colonisation of the colonic mucus gel layer with butyrogenic and hydrogenotropic bacteria in health and ulcerative colitis

Butyrate is the primary energy source for colonocytes and is essential for mucosal integrity and repair. Butyrate deficiency as a result of colonic dysbiosis is a putative factor in ulcerative colitis (UC). Commensal microbes are butyrogenic, while others may inhibit butyrate, through hydrogenotropi...

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Detalles Bibliográficos
Autores principales: Earley, Helen, Lennon, Grainne, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012382/
https://www.ncbi.nlm.nih.gov/pubmed/33790336
http://dx.doi.org/10.1038/s41598-021-86166-6