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Colonisation of the colonic mucus gel layer with butyrogenic and hydrogenotropic bacteria in health and ulcerative colitis
Butyrate is the primary energy source for colonocytes and is essential for mucosal integrity and repair. Butyrate deficiency as a result of colonic dysbiosis is a putative factor in ulcerative colitis (UC). Commensal microbes are butyrogenic, while others may inhibit butyrate, through hydrogenotropi...
Autores principales: | Earley, Helen, Lennon, Grainne, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012382/ https://www.ncbi.nlm.nih.gov/pubmed/33790336 http://dx.doi.org/10.1038/s41598-021-86166-6 |
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