Cargando…
Type I interferons affect the metabolic fitness of CD8(+) T cells from patients with systemic lupus erythematosus
The majority of patients with systemic lupus erythematosus (SLE) have high expression of type I IFN-stimulated genes. Mitochondrial abnormalities have also been reported, but the contribution of type I IFN exposure to these changes is unknown. Here, we show downregulation of mitochondria-derived gen...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012390/ https://www.ncbi.nlm.nih.gov/pubmed/33790300 http://dx.doi.org/10.1038/s41467-021-22312-y |