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Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia

BACKGROUND: Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective hematopoiesis and thus terminate transfusion dependency for formerly transfusion dependant patients. Several miRNAs have been found to r...

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Detalles Bibliográficos
Autores principales: Eltaweel, Noha Hamdy, ElKamah, Ghada Youssef, Khairat, Rabab, Atia, Hanan Abd Elmawgoud, Amr, Khalda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012446/
https://www.ncbi.nlm.nih.gov/pubmed/33788050
http://dx.doi.org/10.1186/s43141-021-00138-x