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Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia
BACKGROUND: Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective hematopoiesis and thus terminate transfusion dependency for formerly transfusion dependant patients. Several miRNAs have been found to r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012446/ https://www.ncbi.nlm.nih.gov/pubmed/33788050 http://dx.doi.org/10.1186/s43141-021-00138-x |