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Humanized Mice Exhibit Exacerbated Abscess Formation and Osteolysis During the Establishment of Implant-Associated Staphylococcus aureus Osteomyelitis

Staphylococcus aureus is the predominant pathogen causing osteomyelitis. Unfortunately, no immunotherapy exists to treat these very challenging and costly infections despite decades of research, and numerous vaccine failures in clinical trials. This lack of success can partially be attributed to an...

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Detalles Bibliográficos
Autores principales: Muthukrishnan, Gowrishankar, Wallimann, Alexandra, Rangel-Moreno, Javier, Bentley, Karen L. de Mesy, Hildebrand, Maria, Mys, Karen, Kenney, H. Mark, Sumrall, Eric T., Daiss, John L., Zeiter, Stephan, Richards, R. Geoff, Schwarz, Edward M., Moriarty, T. Fintan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012494/
https://www.ncbi.nlm.nih.gov/pubmed/33815412
http://dx.doi.org/10.3389/fimmu.2021.651515