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Humanized Mice Exhibit Exacerbated Abscess Formation and Osteolysis During the Establishment of Implant-Associated Staphylococcus aureus Osteomyelitis
Staphylococcus aureus is the predominant pathogen causing osteomyelitis. Unfortunately, no immunotherapy exists to treat these very challenging and costly infections despite decades of research, and numerous vaccine failures in clinical trials. This lack of success can partially be attributed to an...
Autores principales: | Muthukrishnan, Gowrishankar, Wallimann, Alexandra, Rangel-Moreno, Javier, Bentley, Karen L. de Mesy, Hildebrand, Maria, Mys, Karen, Kenney, H. Mark, Sumrall, Eric T., Daiss, John L., Zeiter, Stephan, Richards, R. Geoff, Schwarz, Edward M., Moriarty, T. Fintan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012494/ https://www.ncbi.nlm.nih.gov/pubmed/33815412 http://dx.doi.org/10.3389/fimmu.2021.651515 |
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