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Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease

Alcohol liver disease (ALD) is a major cause of liver-related mortality globally, yet there remains an unmet demand for approved ALD drugs. The pathogenesis of ALD involves perturbations to the intestinal barrier and subsequent translocation of bacterial endotoxin that, acting through toll-like rece...

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Detalles Bibliográficos
Autores principales: Tang, Xiao-Han, Melis, Marta, Mai, Karen, Gudas, Lorraine J., Trasino, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012525/
https://www.ncbi.nlm.nih.gov/pubmed/33815111
http://dx.doi.org/10.3389/fphar.2021.630557