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Growth Hormone/Insulin Growth Factor Axis in Sex Steroid Associated Disorders and Related Cancers

To date, almost all solid malignancies have implicated insulin-like growth factor (IGF) signalling as a driver of tumour growth. However, the remarkable level of crosstalk between sex hormones, the IGF-1 receptor (IGF-1R) and its ligands IGF-1 and 2 in endocrine driven cancers is incompletely unders...

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Detalles Bibliográficos
Autores principales: Bleach, Rachel, Sherlock, Mark, O’Reilly, Michael W., McIlroy, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012538/
https://www.ncbi.nlm.nih.gov/pubmed/33816477
http://dx.doi.org/10.3389/fcell.2021.630503