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New Pathways for the Skin's Stress Response: The Cholinergic Neuropeptide SLURP-1 Can Activate Mast Cells and Alter Cytokine Production in Mice

Background: The alpha7 nicotinic acetylcholine receptor (Chrna7) plays an essential anti-inflammatory role in immune homeostasis and was recently found on mast cells (MC). Psychosocial stress can trigger MC hyperactivation and increases pro-inflammatory cytokines in target tissues such as the skin....

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Detalles Bibliográficos
Autores principales: Ertle, Christoph M., Rommel, Frank R., Tumala, Susanne, Moriwaki, Yasuhiro, Klein, Jochen, Kruse, Johannes, Gieler, Uwe, Peters, Eva M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012551/
https://www.ncbi.nlm.nih.gov/pubmed/33815383
http://dx.doi.org/10.3389/fimmu.2021.631881