Cargando…
New Pathways for the Skin's Stress Response: The Cholinergic Neuropeptide SLURP-1 Can Activate Mast Cells and Alter Cytokine Production in Mice
Background: The alpha7 nicotinic acetylcholine receptor (Chrna7) plays an essential anti-inflammatory role in immune homeostasis and was recently found on mast cells (MC). Psychosocial stress can trigger MC hyperactivation and increases pro-inflammatory cytokines in target tissues such as the skin....
Autores principales: | Ertle, Christoph M., Rommel, Frank R., Tumala, Susanne, Moriwaki, Yasuhiro, Klein, Jochen, Kruse, Johannes, Gieler, Uwe, Peters, Eva M. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012551/ https://www.ncbi.nlm.nih.gov/pubmed/33815383 http://dx.doi.org/10.3389/fimmu.2021.631881 |
Ejemplares similares
-
Anti-Inflammatory Effects of the Nicotinergic Peptides SLURP-1 and SLURP-2 on Human Intestinal Epithelial Cells and Immunocytes
por: Chernyavsky, Alex I., et al.
Publicado: (2014) -
Skin and Psychosomatics – Psychodermatology today
por: Gieler, Uwe, et al.
Publicado: (2020) -
Palmoplantar keratoderma in Slurp2-deficient mice
por: Allan, Christopher M., et al.
Publicado: (2015) -
Parasympathetic Cholinergic and Neuropeptide Mechanisms of Migraine
por: Mikhailov, Nikita, et al.
Publicado: (2016) -
Activation of Mast Cells by Neuropeptides: The Role of Pro-Inflammatory and Anti-Inflammatory Cytokines
por: Lauritano, Dorina, et al.
Publicado: (2023)