Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism

Histone acetylations are important epigenetic markers for transcriptional activation in response to metabolic changes and various stresses. Using the high-throughput SEquencing-Based Yeast replicative Lifespan screen method and the yeast knockout collection, we demonstrate that the HDA complex, a cl...

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Detalles Bibliográficos
Autores principales: Yu, Ruofan, Cao, Xiaohua, Sun, Luyang, Zhu, Jun-yi, Wasko, Brian M, Liu, Wei, Crutcher, Emeline, Liu, Haiying, Jo, Myeong Chan, Qin, Lidong, Kaeberlein, Matt, Han, Zhe, Dang, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012573/
https://www.ncbi.nlm.nih.gov/pubmed/33790287
http://dx.doi.org/10.1038/s41467-021-22257-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012573/
https://www.ncbi.nlm.nih.gov/pubmed/33790287
http://dx.doi.org/10.1038/s41467-021-22257-2

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