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c-Jun N-terminal kinase 1 (JNK1) modulates oligodendrocyte progenitor cell architecture, proliferation and myelination

During Central Nervous System ontogenesis, myelinating oligodendrocytes (OLs) arise from highly ramified and proliferative precursors called oligodendrocyte progenitor cells (OPCs). OPC architecture, proliferation and oligodendro-/myelino-genesis are finely regulated by the interplay of cell-intrins...

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Detalles Bibliográficos
Autores principales: Lorenzati, Martina, Boda, Enrica, Parolisi, Roberta, Bonato, Martino, Borsello, Tiziana, Herdegen, Thomas, Buffo, Annalisa, Vercelli, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012703/
https://www.ncbi.nlm.nih.gov/pubmed/33790350
http://dx.doi.org/10.1038/s41598-021-86673-6