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Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

Bacteria respond to environmental changes by inducing transcription of some genes and repressing others. Sialic acids, which coat human cell surfaces, are a nutrient source for pathogenic and commensal bacteria. The Escherichia coli GntR-type transcriptional repressor, NanR, regulates sialic acid me...

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Detalles Bibliográficos
Autores principales: Horne, Christopher R., Venugopal, Hariprasad, Panjikar, Santosh, Wood, David M., Henrickson, Amy, Brookes, Emre, North, Rachel A., Murphy, James M., Friemann, Rosmarie, Griffin, Michael D. W., Ramm, Georg, Demeler, Borries, Dobson, Renwick C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012715/
https://www.ncbi.nlm.nih.gov/pubmed/33790291
http://dx.doi.org/10.1038/s41467-021-22253-6