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Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
Bacteria respond to environmental changes by inducing transcription of some genes and repressing others. Sialic acids, which coat human cell surfaces, are a nutrient source for pathogenic and commensal bacteria. The Escherichia coli GntR-type transcriptional repressor, NanR, regulates sialic acid me...
Autores principales: | Horne, Christopher R., Venugopal, Hariprasad, Panjikar, Santosh, Wood, David M., Henrickson, Amy, Brookes, Emre, North, Rachel A., Murphy, James M., Friemann, Rosmarie, Griffin, Michael D. W., Ramm, Georg, Demeler, Borries, Dobson, Renwick C. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012715/ https://www.ncbi.nlm.nih.gov/pubmed/33790291 http://dx.doi.org/10.1038/s41467-021-22253-6 |
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