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Extensive-Stage Small Cell Carcinoma Transformation From EGFR Del19-Mutant Lung Adenocarcinoma on Gefitinib at the Twelfth-Year Follow-Up Case Report

INTRODUCTION: The acquired resistance mechanisms in patients with epidermal growth factor receptor (EGFR)-mutant lung cancer, particularly adenocarcinoma (ADC), following treatment with an EGFR tyrosine kinase inhibitor (TKI) have received extensive investigations. The phenotypic transformation to s...

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Detalles Bibliográficos
Autores principales: Kok, Victor C., Lee, Chien-Kuan, Chiang, Yu-Hsin, Wang, Ming-Chih, Lu, Yen-Te, Cherng, Chiu-Chun, Lee, Pei-Yu, Wang, Ke-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012892/
https://www.ncbi.nlm.nih.gov/pubmed/33816221
http://dx.doi.org/10.3389/fonc.2021.564799