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Causal Linkage Between Inflammatory Bowel Disease and Primary Sclerosing Cholangitis: A Two-Sample Mendelian Randomization Analysis

BACKGROUND: Observational studies suggest an association between inflammatory bowel disease (IBD) [including ulcerative colitis (UC) and Crohn’s disease (CD)] and Primary sclerosing cholangitis (PSC), but the causal association between the two diseases remains unclear. METHODS: We used two-sample Me...

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Detalles Bibliográficos
Autores principales: Xie, Ying, Chen, Xuejie, Deng, Minzi, Sun, Yuhao, Wang, Xiaoyan, Chen, Jie, Yuan, Changzheng, Hesketh, Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012893/
https://www.ncbi.nlm.nih.gov/pubmed/33815483
http://dx.doi.org/10.3389/fgene.2021.649376