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SOCS3 Expression by Thymic Stromal Cells Is Required for Normal T Cell Development

The suppressor of cytokine signaling 3 (SOCS3) is a major regulator of immune responses and inflammation as it negatively regulates cytokine signaling. Here, the role of SOCS3 in thymic T cell formation was studied in Socs3(fl/fl) Actin-creER mice (Δsocs3) with a tamoxifen inducible and ubiquitous S...

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Detalles Bibliográficos
Autores principales: Gao, Yu, Liu, Ruining, He, Chenfei, Basile, Juan, Vesterlund, Mattias, Wahren-Herlenius, Marie, Espinoza, Alexander, Hokka-Zakrisson, Cassandra, Zadjali, Fahad, Yoshimura, Akihiko, Karlsson, Mikael, Carow, Berit, Rottenberg, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012910/
https://www.ncbi.nlm.nih.gov/pubmed/33815395
http://dx.doi.org/10.3389/fimmu.2021.642173