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SOCS3 Expression by Thymic Stromal Cells Is Required for Normal T Cell Development
The suppressor of cytokine signaling 3 (SOCS3) is a major regulator of immune responses and inflammation as it negatively regulates cytokine signaling. Here, the role of SOCS3 in thymic T cell formation was studied in Socs3(fl/fl) Actin-creER mice (Δsocs3) with a tamoxifen inducible and ubiquitous S...
Autores principales: | Gao, Yu, Liu, Ruining, He, Chenfei, Basile, Juan, Vesterlund, Mattias, Wahren-Herlenius, Marie, Espinoza, Alexander, Hokka-Zakrisson, Cassandra, Zadjali, Fahad, Yoshimura, Akihiko, Karlsson, Mikael, Carow, Berit, Rottenberg, Martin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012910/ https://www.ncbi.nlm.nih.gov/pubmed/33815395 http://dx.doi.org/10.3389/fimmu.2021.642173 |
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