Pan-Cancer Genome-Wide DNA Methylation Analyses Revealed That Hypermethylation Influences 3D Architecture and Gene Expression Dysregulation in HOXA Locus During Carcinogenesis of Cancers

DNA methylation dysregulation during carcinogenesis has been widely discussed in recent years. However, the pan-cancer DNA methylation biomarkers and corresponding biological mechanisms were seldom investigated. We identified differentially methylated sites and regions from 5,056 The Cancer Genome A...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Liu, Zhenhao, Sun, Xiaomeng, Xia, Xiaoqiong, Liu, Yunhe, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012915/
https://www.ncbi.nlm.nih.gov/pubmed/33816499
http://dx.doi.org/10.3389/fcell.2021.649168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012915/
https://www.ncbi.nlm.nih.gov/pubmed/33816499
http://dx.doi.org/10.3389/fcell.2021.649168

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