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Significance of Crooke's Hyaline Change in Nontumorous Corticotrophs of Patients With Cushing Disease

BACKGROUND: Glucocorticoid excess in Cushing disease (CD) leads to negative feedback suppression, resulting in Crooke's hyaline change (CC) of nontumorous pituitary corticotrophs. We aimed to determine the predictive value of CC of nontumorous corticotrophs in CD. METHODS: The retrospective cha...

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Detalles Bibliográficos
Autores principales: Akirov, Amit, Larouche, Vincent, Shimon, Ilan, Asa, Sylvia L., Mete, Ozgur, Sawka, Anna M., Gentili, Fred, Ezzat, Shereen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013723/
https://www.ncbi.nlm.nih.gov/pubmed/33815279
http://dx.doi.org/10.3389/fendo.2021.620005