Neglecting Plasma Protein Binding in COVID‐19 Patients Leads to a Wrong Interpretation of Lopinavir Overexposure

Boffito et al. recalled the critical importance to correctly interpret protein binding. Changes of lopinavir pharmacokinetics in coronavirus disease 2019 (COVID‐19) are a perfect illustration. Indeed, several studies described that total lopinavir plasma concentrations were considerably higher in pa...

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Detalles Bibliográficos
Autores principales: Stanke‐Labesque, Francoise, Concordet, Didier, Djerada, Zoubir, Bouchet, Stéphane, Solas, Caroline, Mériglier, Etienne, Bonnet, Fabrice, Mourvillier, Bruno, Ruiz, Stéphanie, Martin‐Blondel, Guillaume, Epaulard, Olivier, Schwebel, Carole, Gautier‐Veyret, Elodie, Gandia, Peggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013748/
https://www.ncbi.nlm.nih.gov/pubmed/33547636
http://dx.doi.org/10.1002/cpt.2196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013748/
https://www.ncbi.nlm.nih.gov/pubmed/33547636
http://dx.doi.org/10.1002/cpt.2196

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