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COVID‐19 patients often show high‐titer non‐platelet‐activating anti‐PF4/heparin IgG antibodies

BACKGROUND: Heparin‐induced thrombocytopenia (HIT) is a severe adverse reaction to heparin caused by heparin‐dependent, platelet‐activating anti‐platelet factor 4 (PF4)/heparin antibodies. Heparin is a cornerstone of treatment in critically ill COVID‐19 patients. HIT antibodies can be detected by an...

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Detalles Bibliográficos
Autores principales: Brodard, Justine, Kremer Hovinga, Johanna A., Fontana, Pierre, Studt, Jan‐Dirk, Gruel, Yves, Greinacher, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Journal of Thrombosis and Haemostasis published by ELSEVIER INC. on behalf of International Society on Thrombosis and Haemostasis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013750/
https://www.ncbi.nlm.nih.gov/pubmed/33550713
http://dx.doi.org/10.1111/jth.15262