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PKCα Is Recruited to Staphylococcus aureus-Containing Phagosomes and Impairs Bacterial Replication by Inhibition of Autophagy

Hijacking the autophagic machinery is a key mechanism through which invasive pathogens such as Staphylococcus aureus replicate in their host cells. We have previously demonstrated that the bacteria replicate in phagosomes labeled with the autophagic protein LC3, before escaping to the cytoplasm. Her...

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Detalles Bibliográficos
Autores principales: Gauron, Maria Celeste, Newton, Alexandra C., Colombo, María Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013776/
https://www.ncbi.nlm.nih.gov/pubmed/33815423
http://dx.doi.org/10.3389/fimmu.2021.662987