Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension

Genome haploidization involves sequential loss of cohesin from chromosome arms and centromeres during two meiotic divisions. At centromeres, cohesin's Rec8 subunit is protected from separase cleavage at meiosis I and then deprotected to allow its cleavage at meiosis II. Protection of centromeri...

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Detalles Bibliográficos
Autores principales: Mengoli, Valentina, Jonak, Katarzyna, Lyzak, Oleksii, Lamb, Mahdi, Lister, Lisa M, Lodge, Chris, Rojas, Julie, Zagoriy, Ievgeniia, Herbert, Mary, Zachariae, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013787/
https://www.ncbi.nlm.nih.gov/pubmed/33644894
http://dx.doi.org/10.15252/embj.2020106812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013787/
https://www.ncbi.nlm.nih.gov/pubmed/33644894
http://dx.doi.org/10.15252/embj.2020106812

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