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Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models

Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming. Uric acid (UA), a powerful antioxidant, scavenges reactive oxygen species, wh...

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Detalles Bibliográficos
Autores principales: Kim, Ha Na, Shin, Jin Young, Kim, Dong Yeol, Lee, Ji Eun, Lee, Phil Hyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013923/
https://www.ncbi.nlm.nih.gov/pubmed/33854750
http://dx.doi.org/10.1177/20417314211004816