Cargando…

Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models

Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming. Uric acid (UA), a powerful antioxidant, scavenges reactive oxygen species, wh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ha Na, Shin, Jin Young, Kim, Dong Yeol, Lee, Ji Eun, Lee, Phil Hyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013923/ https://www.ncbi.nlm.nih.gov/pubmed/33854750 http://dx.doi.org/10.1177/20417314211004816

Ejemplares similares

Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models
por: Shin, Jin Young, et al.
Publicado: (2022)

Uric Acid Enhances Neurogenesis in a Parkinsonian Model by Remodeling Mitochondria
por: Lee, Ji Eun, et al.
Publicado: (2022)

Uric acid regulates α-synuclein transmission in Parkinsonian models
por: Shin, Yu Jin, et al.
Publicado: (2023)

The Cleavage Effect of Mesenchymal Stem Cell and Its Derived Matrix Metalloproteinase‐2 on Extracellular α‐Synuclein Aggregates in Parkinsonian Models
por: Oh, Se Hee, et al.
Publicado: (2016)

Feasibility and Efficacy of Intra‐Arterial Administration of Mesenchymal Stem Cells in an Animal Model of Double Toxin‐Induced Multiple System Atrophy
por: Na Kim, Ha, et al.
Publicado: (2017)

Clinical Implications of Cardiac-MIBG SPECT in the Differentiation of Parkinsonian Syndromes
por: Shin, Dong Hoon, et al.
Publicado: (2006)

Elevated Homocysteine by Levodopa Is Detrimental to Neurogenesis in Parkinsonian Model
por: Shin, Jin Young, et al.
Publicado: (2012)

Mesenchymal stem cells stabilize the blood–brain barrier through regulation of astrocytes
por: Park, Hyun Jung, et al.
Publicado: (2015)

Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ
por: Kim, Dae Seong, et al.
Publicado: (2018)

TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells
por: Mead, Ben, et al.
Publicado: (2020)

Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation
por: Angelova, Plamena R., et al.
Publicado: (2017)

Trojan Horse Delivery of 4,4′‐Dimethoxychalcone for Parkinsonian Neuroprotection
por: Zhang, Wenlong, et al.
Publicado: (2021)

Bone Marrow-Derived Mesenchymal Stem Cell Therapy as a Candidate Disease-Modifying Strategy in Parkinson's Disease and Multiple System Atrophy
por: Lee, Phil Hyu, et al.
Publicado: (2009)

Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: Focusing on neuroprotective effects of stromal cell-derived factor-1α
por: Wang, Feifei, et al.
Publicado: (2010)

Dexamethasone priming enhances stemness and immunomodulatory property of tissue-specific human mesenchymal stem cells
por: Rawat, Sonali, et al.
Publicado: (2021)

Engraftment of Mouse Embryonic Stem Cells Differentiated by Default Leads to Neuroprotection, Behaviour Revival and Astrogliosis in Parkinsonian Rats
por: Tripathy, Debasmita, et al.
Publicado: (2013)

Transplantation of Human Neural Stem Cells in a Parkinsonian Model Exerts Neuroprotection via Regulation of the Host Microenvironment
por: Zuo, Fu-Xing, et al.
Publicado: (2015)

Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery
por: Nam, Hyo Suk, et al.
Publicado: (2015)

Small hypoxia-primed mesenchymal stem cells attenuate graft-versus-host disease
por: Kim, YongHwan, et al.
Publicado: (2018)

Correction: Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery
por: Nam, Hyo Suk, et al.
Publicado: (2016)

Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells
por: Lim, Jisun, et al.
Publicado: (2017)

The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys
por: Swanson, Christine R, et al.
Publicado: (2011)

Neuroprotective properties of extracellular vesicles derived from mesenchymal stem cells
por: Jarmalavičiūtė, Akvilė, et al.
Publicado: (2016)

TNF-α Priming Elicits Robust Immunomodulatory Potential of Human Tonsil-Derived Mesenchymal Stem Cells to Alleviate Murine Colitis
por: Shin, Tae-Hoon, et al.
Publicado: (2020)

In vivo priming of human mesenchymal stem cells with hepatocyte growth factor–engineered mesenchymal stem cells promotes therapeutic potential for cardiac repair
por: Park, Bong-Woo, et al.
Publicado: (2020)

Analysis of the Substantia Innominata Volume in Patients with Parkinson’s Disease with Dementia, Dementia with Lewy Bodies, and Alzheimer’s Disease
por: Kim, Hee Jin, et al.
Publicado: (2011)

Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice
por: Kim, Jimin, et al.
Publicado: (2022)

Improvement of Cell Cycle Lifespan and Genetic Damage Susceptibility of Human Mesenchymal Stem Cells by Hypoxic Priming
por: Lee, Chang-Woo, et al.
Publicado: (2018)

Alterations in Energy Metabolism, Neuroprotection and Visual Signal Transduction in the Retina of Parkinsonian, MPTP-Treated Monkeys
por: Campello, Laura, et al.
Publicado: (2013)

Autonomic Dysfunctions in Parkinsonian Disorders
por: Bae, Hyo-Jin, et al.
Publicado: (2009)

Exosome from IFN-γ-Primed Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Improved Skin Inflammation and Barrier Function
por: Yoon, Jin, et al.
Publicado: (2023)

Effect of self-assembled peptide–mesenchymal stem cell complex on the progression of osteoarthritis in a rat model
por: Kim, Ji Eun, et al.
Publicado: (2014)

Pioglitazone-Primed Mesenchymal Stem Cells Stimulate Cell Proliferation, Collagen Synthesis and Matrix Gene Expression in Tenocytes
por: Kim, Won, et al.
Publicado: (2019)

Clinicians’ Tendencies to Under-Rate Parkinsonian Tremors in the Less Affected Hand
por: Lee, Hong Ji, et al.
Publicado: (2015)

IDO and CD40 May Be Key Molecules for Immunomodulatory Capacity of the Primed Tonsil-Derived Mesenchymal Stem Cells
por: Lee, Hyun-Joo, et al.
Publicado: (2021)

A Monoclonal Antibody-GDNF Fusion Protein Is Not Neuroprotective and Is Associated with Proliferative Pancreatic Lesions in Parkinsonian Monkeys
por: Ohshima-Hosoyama, Sachiko, et al.
Publicado: (2012)

Mesenchymal stem cells can modulate longitudinal changes in cortical thickness and its related cognitive decline in patients with multiple system atrophy
por: Sunwoo, Mun Kyung, et al.
Publicado: (2014)

Evaluation of neuroprotective and immunomodulatory properties of mesenchymal stem cells in an ex vivo retinal explant model
por: Reboussin, Élodie, et al.
Publicado: (2022)

Engineered prime editors with PAM flexibility
por: Kweon, Jiyeon, et al.
Publicado: (2021)

Therapeutic Effect of IL1β Priming Tonsil Derived-Mesenchymal Stem Cells in Osteoporosis
por: Yoo, Minjoo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iib43jq05ns1dogjqendejbsjl