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Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy

Emerging reports show that metabolic pathways can be targeted to enhance T cell-mediated immunity to tumors. Yet, tumors consume key metabolites in the host to survive, thus robbing T cells of these nutrients to function and thrive. T cells are often deprived of basic building blocks for energy in t...

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Detalles Bibliográficos
Autores principales: Rangel Rivera, Guillermo O., Knochelmann, Hannah M., Dwyer, Connor J., Smith, Aubrey S., Wyatt, Megan M., Rivera-Reyes, Amalia M., Thaxton, Jessica E., Paulos, Chrystal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014042/
https://www.ncbi.nlm.nih.gov/pubmed/33815400
http://dx.doi.org/10.3389/fimmu.2021.645242