Cargando…
Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy
Emerging reports show that metabolic pathways can be targeted to enhance T cell-mediated immunity to tumors. Yet, tumors consume key metabolites in the host to survive, thus robbing T cells of these nutrients to function and thrive. T cells are often deprived of basic building blocks for energy in t...
Autores principales: | Rangel Rivera, Guillermo O., Knochelmann, Hannah M., Dwyer, Connor J., Smith, Aubrey S., Wyatt, Megan M., Rivera-Reyes, Amalia M., Thaxton, Jessica E., Paulos, Chrystal M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014042/ https://www.ncbi.nlm.nih.gov/pubmed/33815400 http://dx.doi.org/10.3389/fimmu.2021.645242 |
Ejemplares similares
-
Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines
por: Dwyer, Connor J., et al.
Publicado: (2019) -
Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8(+) T cells
por: Dwyer, Connor J., et al.
Publicado: (2020) -
CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies
por: Knochelmann, Hannah M., et al.
Publicado: (2018) -
B cells imprint adoptively transferred CD8(+) T cells with enhanced tumor immunity
por: Smith, Aubrey S, et al.
Publicado: (2022) -
Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies
por: Knochelmann, Hannah M, et al.
Publicado: (2021)