Napabucasin Induces Mouse Bone Loss by Impairing Bone Formation via STAT3

The novel small molecule Napabucasin (also known as BBI608) was shown to inhibit gene transcription driven by Signal Transducer and Activator of Transcription 3 (STAT3), which is considered a promising anticancer target. Many preclinical studies have been conducted in cancer patients examining the s...

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Detalles Bibliográficos
Autores principales: Huang, Xiangru, Jin, Anting, Wang, Xijun, Gao, Xin, Xu, Hongyuan, Chung, Miri, Dai, Qinggang, Yang, Yiling, Jiang, Lingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014090/
https://www.ncbi.nlm.nih.gov/pubmed/33816498
http://dx.doi.org/10.3389/fcell.2021.648866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014090/
https://www.ncbi.nlm.nih.gov/pubmed/33816498
http://dx.doi.org/10.3389/fcell.2021.648866

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