Molecular Dynamics Simulation Study on Allosteric Regulation of CD44-Hyaluronan Binding as a Force Sensing Mechanism

[Image: see text] CD44 protein exists on surfaces of a variety of human cells, acts as a receptor for the hyaluronan (HA) molecule, and mediates cell adhesion via the HA binding in leukocyte trafficking, cell rolling, and so on. The molecular structures of both CD44 and HA are well known, and the pr...

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Detalles Bibliográficos
Autores principales: Lintuluoto, Masami, Horioka, Yota, Hongo, Saki, Lintuluoto, Juha Mikael, Fukunishi, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014924/
https://www.ncbi.nlm.nih.gov/pubmed/33817464
http://dx.doi.org/10.1021/acsomega.0c05502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014924/
https://www.ncbi.nlm.nih.gov/pubmed/33817464
http://dx.doi.org/10.1021/acsomega.0c05502

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