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Radiosensitization by Kinase Inhibition Revealed by Phosphoproteomic Analysis of Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers and known for its extensive genetic heterogeneity, high therapeutic resistance, and strong variation in intrinsic radiosensitivity. To understand the molecular mechanisms underlying radioresistance, we screened the phenoty...

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Detalles Bibliográficos
Autores principales: Wiechmann, Svenja, Saupp, Elena, Schilling, Daniela, Heinzlmeir, Stephanie, Schneider, Günter, Schmid, Roland M., Combs, Stephanie E., Kuster, Bernhard, Dobiasch, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014995/
https://www.ncbi.nlm.nih.gov/pubmed/32651227
http://dx.doi.org/10.1074/mcp.RA120.002046