Construction of a Phenylboronic Acid-Functionalized Nano-Prodrug for pH-Responsive Emodin Delivery and Antibacterial Activity

[Image: see text] In this study, a pH-responsive nano-prodrug was fabricated by conjugating emodin to the PEGylated polyethyleneimine (mPEG-PEI) with acid-sensitive boronate ester bonds. (1)H NMR spectra results showed that emodin was effectively bonded to mPEG-PEI, and acid-sensitive assay further...

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Detalles Bibliográficos
Autores principales: Zheng, Guodong, Zheng, Jiahui, Xiao, Le, Shang, Tongyi, Cai, Yanjun, Li, Yuwei, Xu, Yiming, Chen, Xiaoming, Liu, Yun, Yang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015135/
https://www.ncbi.nlm.nih.gov/pubmed/33817529
http://dx.doi.org/10.1021/acsomega.1c00606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015135/
https://www.ncbi.nlm.nih.gov/pubmed/33817529
http://dx.doi.org/10.1021/acsomega.1c00606

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