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Loss of splicing factor IK impairs normal skeletal muscle development

BACKGROUND: IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the molecular mechanism of IK has been previously reported in vitro, the physiological role of IK has not been fully understood in any animal model. Here, we generate an ik knock-o...

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Detalles Bibliográficos
Autores principales: In Ka, Hye, Seo, Hyemin, Choi, Youngsook, Kim, Joohee, Cho, Mina, Choi, Seok-Yong, Park, Sujeong, Han, Sora, An, Jinsu, Chung, Hak Suk, Yang, Young, Kim, Min Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015194/
https://www.ncbi.nlm.nih.gov/pubmed/33789631
http://dx.doi.org/10.1186/s12915-021-00980-y