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Loss of splicing factor IK impairs normal skeletal muscle development
BACKGROUND: IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the molecular mechanism of IK has been previously reported in vitro, the physiological role of IK has not been fully understood in any animal model. Here, we generate an ik knock-o...
Autores principales: | In Ka, Hye, Seo, Hyemin, Choi, Youngsook, Kim, Joohee, Cho, Mina, Choi, Seok-Yong, Park, Sujeong, Han, Sora, An, Jinsu, Chung, Hak Suk, Yang, Young, Kim, Min Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015194/ https://www.ncbi.nlm.nih.gov/pubmed/33789631 http://dx.doi.org/10.1186/s12915-021-00980-y |
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