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Mutant p53 regulates Survivin to foster lung metastasis
Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers worldwide and evolves often to lung metastasis. P53(R175H) (homologous to Trp53(R172H) in mice) is a common hot spot mutation. How metastasis is regulated by p53(R175H) in ESCC remains to be investigated. To investigate p53(...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015716/ https://www.ncbi.nlm.nih.gov/pubmed/33737385 http://dx.doi.org/10.1101/gad.340505.120 |