Mutant p53 regulates Survivin to foster lung metastasis

Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers worldwide and evolves often to lung metastasis. P53(R175H) (homologous to Trp53(R172H) in mice) is a common hot spot mutation. How metastasis is regulated by p53(R175H) in ESCC remains to be investigated. To investigate p53(...

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Detalles Bibliográficos
Autores principales: Tang, Qiaosi, Efe, Gizem, Chiarella, Anna M., Leung, Jessica, Chen, Maoting, Yamazoe, Taiji, Su, Zhenyi, Pitarresi, Jason R., Li, Jinyang, Islam, Mirazul, Karakasheva, Tatiana, Klein-Szanto, Andres J., Pan, Samuel, Hu, Jianhua, Natsugoe, Shoji, Gu, Wei, Stanger, Ben Z., Wong, Kwok-K, Diehl, J. Alan, Bass, Adam J., Nakagawa, Hiroshi, Murphy, Maureen E., Rustgi, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015716/
https://www.ncbi.nlm.nih.gov/pubmed/33737385
http://dx.doi.org/10.1101/gad.340505.120

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