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Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity

In addition to susceptibility to infections, conventional primary immunodeficiency disorders (PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as lymphoproliferative and/or autoimmune disease. Autoimmunity can be the prominent phenotype of PIDs and commonly inclu...

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Detalles Bibliográficos
Autores principales: Sogkas, Georgios, Atschekzei, Faranaz, Adriawan, Ignatius Ryan, Dubrowinskaja, Natalia, Witte, Torsten, Schmidt, Reinhold Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015752/
https://www.ncbi.nlm.nih.gov/pubmed/33795850
http://dx.doi.org/10.1038/s41423-020-00626-z