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Emerging Therapeutic Strategies to Restore Regulatory T Cell Control of Islet Autoimmunity in Type 1 Diabetes

Despite many decades of investigation uncovering the autoimmune mechanisms underlying Type 1 Diabetes (T1D), translating these findings into effective therapeutics has proven extremely challenging. T1D is caused by autoreactive T cells that become inappropriately activated and kill the β cells in th...

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Detalles Bibliográficos
Autores principales: Volfson-Sedletsky, Victoria, Jones, Albert, Hernandez-Escalante, Jaileene, Dooms, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015774/
https://www.ncbi.nlm.nih.gov/pubmed/33815387
http://dx.doi.org/10.3389/fimmu.2021.635767