Cargando…
Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver
The adult liver has an exceptional ability to regenerate, but how it maintains its specialized functions during regeneration is unclear. Here, we used partial hepatectomy (PHx) in tandem with single-cell transcriptomics to track cellular transitions and heterogeneities of ∼22,000 liver cells through...
Autores principales: | Chembazhi, Ullas V., Bangru, Sushant, Hernaez, Mikel, Kalsotra, Auinash |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015853/ https://www.ncbi.nlm.nih.gov/pubmed/33649154 http://dx.doi.org/10.1101/gr.267013.120 |
Ejemplares similares
-
SAT007 Excess Bile Acids Can Compensate To Promote Regeneration In Constitutive Androstane Receptor Knockout Mice
por: Zhou, Weinan, et al.
Publicado: (2023) -
SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes
por: Peng, Jianhao, et al.
Publicado: (2022) -
Advances in analyzing RNA diversity in eukaryotic transcriptomes: peering through the Omics lens
por: Bangru, Sushant, et al.
Publicado: (2016) -
PTBP1 controls intestinal epithelial regeneration through post-transcriptional regulation of gene expression
por: Chembazhi, Ullas Valiya, et al.
Publicado: (2023) -
Alternative Splicing Rewires Hippo Signaling Pathway in Hepatocytes to Promote Liver Regeneration
por: Bangru, Sushant, et al.
Publicado: (2018)