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Orc4 spatiotemporally stabilizes centromeric chromatin

The establishment of centromeric chromatin and its propagation by the centromere-specific histone CENPA is mediated by epigenetic mechanisms in most eukaryotes. DNA replication origins, origin binding proteins, and replication timing of centromere DNA are important determinants of centromere functio...

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Detalles Bibliográficos
Autores principales: Sreekumar, Lakshmi, Kumari, Kiran, Guin, Krishnendu, Bakshi, Asif, Varshney, Neha, Thimmappa, Bhagya C., Narlikar, Leelavati, Padinhateeri, Ranjith, Siddharthan, Rahul, Sanyal, Kaustuv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015856/
https://www.ncbi.nlm.nih.gov/pubmed/33514624
http://dx.doi.org/10.1101/gr.265900.120