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Alignment of single-cell RNA-seq samples without overcorrection using kernel density matching

Single-cell RNA sequencing (scRNA-seq) technology is poised to replace bulk cell RNA sequencing for many biological and medical applications as it allows users to measure gene expression levels in a cell type–specific manner. However, data produced by scRNA-seq often exhibit batch effects that can b...

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Detalles Bibliográficos
Autores principales: Chen, Mengjie, Zhan, Qi, Mu, Zepeng, Wang, Lili, Zheng, Zhaohui, Miao, Jinlin, Zhu, Ping, Li, Yang I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015859/
https://www.ncbi.nlm.nih.gov/pubmed/33741686
http://dx.doi.org/10.1101/gr.261115.120