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RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells

The therapeutic approach of liver fibrosis is still an unsolved clinical problem worldwide. Notably, the accumulation of extracellular matrix (ECM) in the liver is mediated by the production of cytokines and growth factors, such as transforming growth factor-β1 (TGF-β1) in hepatic stellate cells (HS...

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Detalles Bibliográficos
Autores principales: Yan, Qi, Pan, Linxin, Qi, Shunli, Liu, Fang, Wang, Zhen, Qian, Cheng, Chen, Lijian, Du, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015948/
https://www.ncbi.nlm.nih.gov/pubmed/33816485
http://dx.doi.org/10.3389/fcell.2021.634902