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Evaluation and modulation of DNA lesion bypass in an SV40 large T antigen‐based in vitro replication system

DNA damage removal by nucleotide excision repair (NER) and replicative bypass via translesion synthesis (TLS) and template switch (TSw) are important in ensuring genome stability. In this study, we tested the applicability of an SV40 large T antigen‐based replication system for the simultaneous exam...

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Detalles Bibliográficos
Autores principales: Szeltner, Zoltán, Póti, Ádám, Harami, Gábor M., Kovács, Mihály, Szüts, Dávid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016126/
https://www.ncbi.nlm.nih.gov/pubmed/33512058
http://dx.doi.org/10.1002/2211-5463.13099