Cargando…

Lysine 268 adjacent to transmembrane helix 5 of hamster P‐glycoprotein is the major photobinding site of iodomycin in CHO B30 cells

P‐glycoprotein (Pgp) detoxifies cells by exporting hundreds of chemically dissimilar hydrophobic and amphipathic compounds and is implicated in multidrug resistance (MDR) in the treatment of cancers. Photoaffinity labeling of plasma membrane vesicles of MDR CHO B30 cells with the anthracycline [(125...

Descripción completa

Detalles Bibliográficos
Autores principales:	Demmer, Annette, Thole, Hubert, Raida, Manfred, Tümmler, Burkhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016128/ https://www.ncbi.nlm.nih.gov/pubmed/33565718 http://dx.doi.org/10.1002/2211-5463.13112

Ejemplares similares

Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies
por: Molins-Molina, Oscar, et al.
Publicado: (2019)

Effect of anthracycline analogs on photolabelling of p-glycoprotein by [125I]iodomycin and [3H]azidopine: relation to lipophilicity and inhibition of daunorubicin transport in multidrug resistant cells.
por: Friche, E., et al.
Publicado: (1993)

A method for genome-wide analysis of DNA helical tension by means of psoralen–DNA photobinding
por: Bermúdez, Ignacio, et al.
Publicado: (2010)

Transmembrane helix: simple or complex
por: Wong, Wing-Cheong, et al.
Publicado: (2012)

Atomistic mechanism of transmembrane helix association
por: Domański, Jan, et al.
Publicado: (2020)

Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing
por: Bañó-Polo, Manuel, et al.
Publicado: (2012)

Hydrophobic pulses predict transmembrane helix irregularities and channel transmembrane units
por: Paulet, Damien, et al.
Publicado: (2011)

Active machine learning for transmembrane helix prediction
por: Osmanbeyoglu, Hatice U, et al.
Publicado: (2010)

Isolation and characterisation of exosomes from Chinese hamster ovary (CHO) cells
por: Skrika-Alexopoulos, Eleftheria, et al.
Publicado: (2023)

Balancing Force Field Protein–Lipid Interactions To Capture Transmembrane Helix–Helix Association
por: Domański, Jan, et al.
Publicado: (2018)

Prediction of transmembrane helix orientation in polytopic membrane proteins
por: Adamian, Larisa, et al.
Publicado: (2006)

The role of hydrophobic matching on transmembrane helix packing in cells
por: Grau, Brayan, et al.
Publicado: (2017)

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line
por: Xu, Xun, et al.
Publicado: (2011)

A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity
por: Yao, Grace, et al.
Publicado: (2021)

Hydrophobic mismatch and sequence specificity compete when transmembrane helix-helix interactions are measured with the TOXCAT assay
por: Hellmann, Nadja, et al.
Publicado: (2022)

TMM@: a web application for the analysis of transmembrane helix mobility
por: Skjaerven, Lars, et al.
Publicado: (2007)

The Roles of Transmembrane Domain Helix-III during Rhodopsin Photoactivation
por: Ou, Wen-bin, et al.
Publicado: (2011)

Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR
por: Corradi, Valentina, et al.
Publicado: (2018)

Impact of Differential Detergent Interactions on Transmembrane Helix Dimerization Affinities
por: Qureshi, Tabussom, et al.
Publicado: (2016)

Principal component analysis of alpha-helix deformations in transmembrane proteins
por: Bevacqua, Alexander, et al.
Publicado: (2021)

SYNCHRONIZATION OF MITOCHONDRIAL DNA SYNTHESIS IN CHINESE HAMSTER CELLS (LINE CHO) DEPRIVED OF ISOLEUCINE
por: Ley, Kenneth D., et al.
Publicado: (1973)

Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines
por: Veith, Nathalie, et al.
Publicado: (2016)

Health Tract, No. 268: Adulterations
Publicado: (1867)

N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins
por: Sweeting, Braden, et al.
Publicado: (2013)

A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells
por: Shamie, Isaac, et al.
Publicado: (2021)

TMPad: an integrated structural database for helix-packing folds in transmembrane proteins
por: Lo, Allan, et al.
Publicado: (2011)

SPONTANEOUS TRANSMEMBRANE HELIX INSERTION THERMODYNAMICALLY MIMICS TRANSLOCON-GUIDED INSERTION
por: Ulmschneider, Martin B., et al.
Publicado: (2014)

Discovered by genomics: putative reductive dehalogenases with N-terminus transmembrane helixes
por: Atashgahi, Siavash
Publicado: (2019)

Structure of the Membrane Anchor of Pestivirus Glycoprotein E(rns), a Long Tilted Amphipathic Helix
por: Aberle, Daniel, et al.
Publicado: (2014)

Transmembrane signaling and cytoplasmic signal conversion by dimeric transmembrane helix 2 and a linker domain of the DcuS sensor kinase
por: Stopp, Marius, et al.
Publicado: (2020)

Data for engineering lipid metabolism of Chinese hamster ovary (CHO) cells for enhanced recombinant protein production
por: Budge, James D., et al.
Publicado: (2020)

Engineering of CHO Cells for the Production of Recombinant Glycoprotein Vaccines with Xylosylated N-glycans
por: Sandig, Grit, et al.
Publicado: (2017)

Predicting Residue-Residue Contacts and Helix-Helix Interactions in Transmembrane Proteins Using an Integrative Feature-Based Random Forest Approach
por: Wang, Xiao-Feng, et al.
Publicado: (2011)

Transmembrane biogenesis of the vesicular stomatitis virus glycoprotein
Publicado: (1979)

Transmembrane Helix Dynamics of Bacterial Chemoreceptors Supports a Piston Model of Signalling
por: Hall, Benjamin A., et al.
Publicado: (2011)

Coupling of Transmembrane Helix Orientation To Membrane Release of the Juxtamembrane Region in FGFR3
por: Tamagaki, Hiroko, et al.
Publicado: (2014)

Sequence-Specific Dimerization of a Transmembrane Helix in Amphipol A8-35
por: Stangl, Michael, et al.
Publicado: (2014)

Influence of Transmembrane Helix Mutations on Cytochrome P450-Membrane Interactions and Function
por: Mustafa, Ghulam, et al.
Publicado: (2019)

Illuminating Disorder Induced by Glu in a Stable Arg-Anchored Transmembrane Helix
por: Price, Jake R., et al.
Publicado: (2021)

268 DEGAS: Deep transfer learning reveals cancer-like transcriptional signatures in histologically normal prostate tissue and adjacent-normal tissues in pancreatic cancer
por: Couetil, Justin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t7335o60h5dj1jd0pt07idjain