Rab44 isoforms similarly promote lysosomal exocytosis, but exhibit differential localization in mast cells

Rab44 is a large Rab GTPase containing a Rab GTPase domain and some additional N‐terminal domains. We recently used Rab44‐deficient mice to demonstrate that Rab44 regulates granule exocytosis in mast cells and IgE‐mediated anaphylaxis. In mouse mast cells, Rab44 is expressed as two isoforms, namely,...

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Detalles Bibliográficos
Autores principales: Kadowaki, Tomoko, Yamaguchi, Yu, Ogawa, Kohei, Tokuhisa, Mitsuko, Okamoto, Kuniaki, Tsukuba, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016136/
https://www.ncbi.nlm.nih.gov/pubmed/33641252
http://dx.doi.org/10.1002/2211-5463.13133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016136/
https://www.ncbi.nlm.nih.gov/pubmed/33641252
http://dx.doi.org/10.1002/2211-5463.13133

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