Independent domains for recruitment of PRC1 and PRC2 by human XIST

XIST establishes inactivation across its chromosome of origin, even when expressed from autosomal transgenes. To identify the regions of human XIST essential for recruiting heterochromatic marks we generated a series of overlapping deletions in an autosomal inducible XIST transgene present in 8p of...

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Detalles Bibliográficos
Autores principales: Dixon-McDougall, Thomas, Brown, Carolyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016261/
https://www.ncbi.nlm.nih.gov/pubmed/33750950
http://dx.doi.org/10.1371/journal.pgen.1009123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016261/
https://www.ncbi.nlm.nih.gov/pubmed/33750950
http://dx.doi.org/10.1371/journal.pgen.1009123

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